SpotXplore: a Cytoscape plugin for visual exploration of hotspot expression in gene regulatory networks

نویسندگان

  • Michel A. Westenberg
  • Jos B. T. M. Roerdink
  • Oscar P. Kuipers
  • Sacha A. F. T. van Hijum
چکیده

UNLABELLED SpotXplore is a plugin for Cytoscape for extraction and visualization of differentially expressed subnetworks (hotspots) from gene networks. The hotspot-based visualization approach enables interactive exploration of regulatory interactions in differentially expressed gene sets, and it allows a researcher to explore gene expression in direct relation to the affected cellular gene network. The hotspots provide a view beyond the commonly used metabolic pathways and gene ontologies. AVAILABILITY http://www.win.tue.nl/∼mwestenb/spotxplore/.

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عنوان ژورنال:

دوره 26  شماره 

صفحات  -

تاریخ انتشار 2010